Thermo Fisher Scientific Bmf Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive control: K562
• Predicted reactivity: Mouse (87%), Rat (87%), Bovine (91%)
• IHC notes: Requires antigen retrieval using heat-mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene belongs to the BCL2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities.
This protein contains a single BCL2 homology domain 3 (BH3), binds BCL2 proteins, and functions as an apoptotic activator. It is sequestered to myosin V motors through association with dynein light chain 2, which may help sense intracellular damage and trigger apoptosis.
Alternatively spliced transcript variants encoding different isoforms have been identified.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.