Thermo Fisher Scientific YBX1 Polyclonal Antibody
YBX1 단백질을 인식하는 Rabbit Polyclonal 항체로 WB, IHC, Flow Cytometry에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제. 동결건조 형태, PBS/trehalose 버퍼, -20°C 보관.
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Thermo Fisher Scientific YBX1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–5 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg/1×10^6 cells |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human YB1 (137–152aa: KYAADRNHYRRYPRRR) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747355 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. It stabilizes cytoplasmic mRNA and modulates translation by interacting with eukaryotic initiation factors. This protein binds promoters containing a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes, regulating transcription of numerous genes. It promotes separation of mismatched or cisplatin-modified DNA strands, exhibits endonucleolytic activity introducing nicks or breaks into double-stranded DNA (in vitro), and may play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-80241_YBX1_P67809-1_Rabbit.svg, PA5-80241_YBX1_P67809-1_Rabbit_PDP.jpeg)
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