Thermo Fisher Scientific FANCM Polyclonal Antibody
Rabbit polyclonal antibody against human FANCM protein. Validated for ICC/IF applications. Antigen affinity purified and supplied as liquid in PBS with glycerol. Suitable for research use in DNA repair and Fanconi anemia pathway studies.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FANCM. Recombinant protein control fragment (Product # RP-106606) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663992 |
Product Specific Information
Immunogen sequence:
LAGTHTSLRLP QEGKGTCILV GGHEITSGLE VISSLRAIHG LQVEVCPLNG CDYIVSNRMV VERRSQSEML NSVNKNKFIE QIQH
Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 69%
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
Members of the FANC group are related by their assembly into a common nuclear protein complex.
This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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