Thermo Fisher Scientific ORAI2 Polyclonal Antibody
Rabbit polyclonal antibody against human ORAI2 protein. Validated for ICC/IF applications at 0.25–2 µg/mL. Provides high specificity and affinity through antigen affinity purification. Supplied in PBS with 40% glycerol for stable storage. For research ...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ORAI2. Recombinant protein control fragment (Product # RP-106605) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664494 |
Product Specific Information
Immunogen sequence:
MSAELNVPIDP SAPACPEPGH KGMDYRDWVR RSYLELVTSN HHSVQALSW
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
Antigen stimulation of immune cells triggers Ca²⁺ entry through Ca²⁺ release-activated Ca²⁺ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a four-transmembrane spanning protein essential for CRAC channel function. ORAI2 functions as a highly selective Ca²⁺ plasma membrane channel gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca²⁺ sensor, though with lesser efficacy than ORAI1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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