Thermo Fisher Scientific MMP10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_0024161) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MMP10,uniProtId:P09238-1,ncbiNodeId:9606,antigenRange:237-476,antigenLength:476,antigenImageFileName:PA5-120847_MMP10_P09238-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120847_MMP10_P09238-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.93 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914419

Product Specific Information

Positive test controls include: BT-474, MCF7, U-251MG, M21. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.

Immunogen sequence: PLYNSFTELA QFRLSQDDVN GIQSLYGPPP ASTEEPLVPT KSVPSGSEMP AKCDPALSFD AISTLRGEYL FFKDRYFWRR SHWNPEPEFH LISAFWPSLP SYLDAAYEVN SRDTVFIFKG NEFWAIRGNE VQAGYPRGIH TLGFPPTIRK IDAAVSDKEK KKTYFFAADK YWRFDENSQS MEQGFPRLIA DDFPGVEPKV DAVLQAFGFF YFFSGSSQFE FDPNARMVTH ILKSNSWLHC

Target Information

MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.