Thermo Fisher Scientific MMP11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MMP11,uniProtId:P24347-1,ncbiNodeId:9606,antigenRange:239-488,antigenLength:488,antigenImageFileName:PA5-120848_MMP11_P24347-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120848_MMP11_P24347-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.59 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914420

Product Specific Information

Positive test controls include: Raji, 293T, Mouse lung, Mouse kidney, Mouse skeletal muscle, Mouse ovary, Mouse heart. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.

Immunogen sequence: FRYPLSLSPD DCRGVQHLYG QPWPTVTSRT PALGPQAGID TNEIAPLEPD APPDACEASF DAVSTIRGEL FFFKAGFVWR LRGGQLQPGY PALASRHWQG LPSPVDAAFE DAQGHIWFFQ GAQYWVYDGE KPVLGPAPLT ELGLVRFPVH AALVWGPEKN KIYFFRGRDY WRFHPSTRRV DSPVPRRATD WRGVPSEIDA AFQDADGYAY FLRGRLYWKF DPVKVKALEG FPRLVGPDFF GCAEPANTFL

Target Information

Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.