Thermo Fisher Scientific LL-37 Polyclonal Antibody
LL-37 인간 Cathelicidin 항균 펩타이드에 특이적인 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Cathelicidin conjugated to blue carrier protein has been used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infections in the skin.
Beyond antimicrobial activity, Cathelicidins mediate innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment.
Cathelicidin antimicrobial peptides serve as prototypes for innovative drugs that may treat infection and/or modulate immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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