Thermo Fisher Scientific ERK1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.

Target Information

MAPK3 (ERK1) is a serine/threonine kinase that activates p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
ERK1 is widely expressed and regulates meiosis, mitosis, and post-mitotic functions in differentiated cells.
It is activated by various stimuli including growth factors, cytokines, virus infection, and G protein-coupled receptor ligands.
Functionally, ERK1 regulates cellular processes such as proliferation, differentiation, and cell cycle progression.
Activated ERK1 translocates to the nucleus to phosphorylate nuclear targets.
Alternatively spliced transcript variants encoding different isoforms of ERK1 have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.