Thermo Fisher Scientific FGFR4 Polyclonal Antibody
FGFR4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간과 마우스 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C 이하에서 보관 권장.
- 카탈로그번호
- PA5119550
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human FGFR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913123 |
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.
Target Information
FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family regulates various cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury.
FGFR4 is required for normal down-regulation of CYP7A1 expression, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It also plays a role in postnatal lung development and may be involved in skeletal muscle cell lineage development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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