Thermo Fisher Scientific AVPR1B Polyclonal Antibody
AVPR1B 단백질에 특이적인 Thermo Fisher Scientific의 rabbit polyclonal antibody로, Human, Mouse, Rat에 반응합니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 높은 순도(>95%)로 정제되어 연구용으로 적합합니다.
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Thermo Fisher Scientific AVPR1B Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 300–350 of Human V1b Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719103 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. The purity is greater than 95% as confirmed by SDS-PAGE.
Target Information
Vasopressin V1B receptor expression has been observed in pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a common structure of seven membrane-spanning helices.
GPCRs exist in both active and inactive forms, and their activation leads to signaling through G-proteins and downstream effectors.
Research continues to explore the mechanisms of GPCR regulation and its implications for drug development, with notable examples including Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-75375_AVPR1B_P47901-1_Rabbit.svg, PA5-75375_AVPR1B_P47901-1_Rabbit_PDP.jpeg)
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