Thermo Fisher Scientific MYL9/MYL12 Recombinant Rabbit Monoclonal Antibody (AWBMyl9F6 (F-6))
MYL9/MYL12 단백질을 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 재현성을 제공. IHC, ELISA, 기능 분석 등 다양한 연구용 응용 가능. HEK293 세포에서 발현된 액상형 항체로, 일관된 품질과 동물 유래 성분 없는 제형 제공.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Functional Assay
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AWBMyl9F6 (F-6) |
| Immunogen | N-terminal peptide of Myl9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744997 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
Myosin regulatory light polypeptide 9 (MYL9) is a highly conserved, ubiquitously expressed protein encoded by the MYL9 gene in humans. Myosin is a structural component of muscle composed of two heavy chains and four light chains, including phosphorylatable and nonphosphorylatable subunits.
MYL9 may regulate muscle contraction by modulating the ATPase activity of myosin heads. MYL9 and MYL12 act as functional ligands for CD69, and blockade of CD69-MYL9/12 interaction ameliorates allergic airway inflammation in mouse models of asthma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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