Thermo Fisher Scientific MEF2C Monoclonal Antibody (OTI4F7), TrueMAB
MEF2C 단백질을 인식하는 Mouse Monoclonal Antibody로, Western blot, IHC, ICC, Flow Cytometry에 사용 가능. 인간 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer에 8% trehalose 포함, -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F7 |
| Immunogen | Full length human recombinant protein of human MEF2C produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MEF2C is a transcription activator that binds specifically to the MEF2 element in regulatory regions of many muscle-specific genes. It controls cardiac morphogenesis, myogenesis, and vascular development, and plays a key role in hippocampal-dependent learning and memory by regulating synaptic transmission. MEF2C is crucial for neuronal development, megakaryocyte and platelet formation, and bone marrow B lymphopoiesis. It is also required for B-cell survival, proliferation, and normal germinal center formation. Isoforms lacking the repressor domain (isoform 3 and 4) are more active than isoform 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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