Thermo Fisher Scientific Integrase interactor 1 (INI-1)/SNF5/SMARCB1 Recombinant Rabbit Monoclonal Antibody (SMARCB1/4587R)
Recombinant rabbit monoclonal antibody targeting INI-1/SNF5/SMARCB1 for IHC applications. Reacts with human and mouse samples. High purity via Protein A/G purification. Supplied as liquid, 200 µg/mL in PBS with BSA and sodium azide. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SMARCB1/4587R |
| Immunogen | Human full-length INI1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SWI-SNF complex is involved in the activation of transcription via remodeling of nucleosome structure in an ATP-dependent manner. Brm (SNF2α) and Brg-1 (SNF2β) are ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also known as SNF5), BAF155 (SRG3), and BAF170 comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155, and BAF170 to Brg-1 increases remodeling activity. Other subunits play regulatory roles. hSNF2L and hSNF2H are homologs of Drosophila ISWI, found in chromatin remodeling complexes other than SWI/SNF, including NURF (nucleosome remodeling factor).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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