Thermo Fisher Scientific CD19 Monoclonal Antibody (OTI1F9), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also be present on myeloid leukemia cells, particularly of monocytic lineage. CD19 serves as an important functional regulator of normal and malignant B cell proliferation and is expressed in all B cell precursor leukemias.
As a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 lowers the activation threshold for antigen receptor-dependent stimulation and can also signal independently. Mutations in the CD19 gene can cause hypogammaglobulinemia, while overexpression leads to B cell hyperactivity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.