Thermo Fisher Scientific CD19 Monoclonal Antibody (OTI2F6), TrueMAB
CD19 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능. 인간 시료 반응성, 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F6 |
| Immunogen | Full length human recombinant protein of human CD19 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also be expressed on myeloid leukemia cells, particularly of monocytic lineage. CD19 acts as a signal-amplifying coreceptor for the B cell receptor (BCR) and plays a key role in regulating B cell activation and proliferation.
Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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