Thermo Fisher Scientific RAD17 Polyclonal Antibody
RAD17 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 유세포분석에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간 RAD17 단백질의 N-말단 합성 펩타이드로부터 제작됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Flow Cytometry (Flow) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to a N-terminal region of human RAD17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568697 |
Product Specific Information
- Suggested positive control: antigen standard for RAD17 (transient overexpression lysate).
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.
It has a weak ATPase activity required for chromatin binding and participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, as well as CHEK1 activation.
Rad17 may also serve as a sensor of DNA replication progression and be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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