Thermo Fisher Scientific KLHL21 Monoclonal Antibody (2H4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2H4

Immunogen

Purified recombinant fragment of human KLHL21 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10983749

Product Specific Information

MA5-15654 targets KLHL21 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.

The MA5-15654 immunogen is purified recombinant fragment of human KLHL21 expressed in E. Coli.
.

MA5-15654 detects KLHL21 which has a predicted molecular weight of approximately 66kDa.

Target Information

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.