Thermo Fisher Scientific Phospho-Histone H3 (Ser11) Polyclonal Antibody
Histone H3의 Ser11 위치에 인산화된 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. 고순도 정제 및 안정적인 PBS/glycerol buffer로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Insect, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Histone H3 (Accession P68431), corresponding to amino acid residues around phosphorylated Ser11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816409 |
Product Specific Information
Antibody detects endogenous levels of Histone H3 only when phosphorylated at Serine 11.
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with other core histones, it forms the nucleosome structure that organizes DNA. Histones are essential for transcription regulation, DNA repair, replication, and chromosomal stability.
Post-translational modifications such as methylation, acetylation, and phosphorylation of the N-terminal tail of histone H3 influence chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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