Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI3D11), TrueMAB
인간 APOBR 단백질(aa 780-1088)을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화(1:2,000 희석). 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL of distilled water to achieve a final concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Macrophage receptor that binds to apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or similar domains of APOB in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL).
Functions in internalization of TRL and may contribute to lipid supply for reticuloendothelial cells and foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions.
Mediates rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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