Thermo Fisher Scientific Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Monoclonal Antibody (C.795.3)
Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) 단일클론 항체로, 인간 및 랫트 시료에 반응합니다. Western blot과 Immunoprecipitation에 적합하며, 고순도의 Affinity chromatography 정제 항체입니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.795.3 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr674/675 of human TrkA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 36 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10986069 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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