Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI1E11), TrueMAB
인간 DOCK8 단백질(aa 84-405)을 항원으로 제작된 Mouse IgG2b 단클론 항체. Western blot에 최적화되어 있으며, 무보존제 상태의 동결건조 형태로 제공. 연구용으로 면역 반응 및 B 세포 시냅스 형성 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 84–405 of human DOCK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The Dedicator of Cytokinesis Protein 8 (DOCK8) belongs to the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 is essential for humoral immune responses and proper formation of the B cell immunological synapse.
Mutations in DOCK8 cause the autosomal recessive form of hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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