Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI20G10), TrueMAB

Applications

Western Blot (WB)

• Assay-dependent

Flow Cytometry (Flow)

• 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family and binds specifically to the programmed death receptor 1 (PD-1). This interaction negatively regulates T-cell receptor (TCR) signaling, reducing TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed on various murine and human cancers and can be upregulated by IFN-γ stimulation, suggesting a key role in tumor immune evasion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.