Thermo Fisher Scientific Acidic Cytokeratin Monoclonal Antibody (OTI9H3), TrueMAB
인간 세포에서 산성 케라틴을 인식하는 단클론 항체로, IHC(P)에서 1:150 희석으로 사용 가능. 합성 펩타이드 면역원 기반이며, 동결건조 형태로 제공. 종양 진단 연구 및 세포 분화 연구에 활용 가능.
- 카탈로그번호
- CF190248
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9H3 |
| Immunogen | Synthetic peptide corresponding to the conserved region of human type I (Acidic) keratins (including KRT9, KRT10, KRT12, KRT13, KRT14, KRT15, KRT16, KRT17, KRT18, KRT19, KRT20) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Synthetic peptide sequence: EKVTMQNLND RLASYLDKVR ALEEAN
- For reconstitution: Add 100 µL distilled water to obtain ~1 mg/mL antibody concentration.
- For conjugation experiments: Perform desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Cytokeratin pan is a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins range in molecular weight between 40–68 kDa, with isoelectric points between 4.9–7.8.
Expression patterns of cytokeratin subtypes vary among epithelial tissues and relate to the degree of differentiation.
These patterns are valuable in distinguishing epithelial malignancies, aiding tumor diagnosis through immunohistochemistry, cytopathology, and flow cytometry.
Keratin expression serves as a useful marker in cancer research and tumor diagnostics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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