Thermo Fisher Scientific PKM2 Monoclonal Antibody (OTI1A1), TrueMAB
PKM2 단백질을 인식하는 단클론 항체로, IHC(P) 등 다양한 응용에 적합. 인간 시료 반응성, Mouse IgG2a 아이소타입. 합성 펩타이드 면역원 기반, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A1 |
| Immunogen | Synthetic peptide corresponding to the region encoded by PKM gene M2 isoform |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Synthetic peptide sequence: LRRLAPITSDPTEATAVGAV
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PKM2 (Pyruvate Kinase M2) catalyzes the conversion of phosphoenolpyruvate to pyruvate and ATP. It interacts with thyroid hormone, mediating metabolic effects, and binds to bacterial Opa protein, suggesting a role in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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