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Thermo Fisher Scientific Cofilin-1 Polyclonal Antibody
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Cofilin-1 인산화 및 비인산화 형태 모두 인식하는 Sheep Polyclonal Antibody. WB 및 IHC에 사용 가능하며 인간, 마우스, 랫트 반응성. PBS 버퍼에 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적.
- 카탈로그번호
- OSC00053G-500UG
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 09:35
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific OSC00053G-500UG Cofilin-1 Polyclonal Antibody 500 ug pk판매 단위 pk ·
재고 확인 필요
723,400원VAT 포함 795,740원
Thermo Fisher Scientific · Thermo Fisher Scientific Cofilin-1 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from phospho Y140 & S156 of human Cofilin-1 (non-muscle isoform) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Antigen is homologous in rat, mouse, and monkey.
- Specificity: Cofilin-1; recognizes both phosphorylated and unphosphorylated forms.
Target Information
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics, essential for mitosis and cytokinesis. Plays a role in cell morphology and cytoskeletal organization. Required for up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, enhancing chemokine uptake and degradation. Also involved in neural tube morphogenesis and neural crest cell migration.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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