Thermo Fisher Scientific Cofilin-1 Polyclonal Antibody
Cofilin-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 내부 영역 합성 펩타이드 면역원 사용. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C에서 안정적.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: Cofilin-1.
Target Information
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity.
Regulates actin cytoskeleton dynamics, essential for normal mitosis and cytokinesis.
Plays a role in cell morphology and cytoskeletal organization.
Required for the up-regulation of atypical chemokine receptor ACKR2, enhancing chemokine uptake and degradation.
Involved in neural tube morphogenesis and neural crest cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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