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Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody
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Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody

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Cofilin-1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간, 마우스, 랫트에 반응하며 비결합형 상태로 제공. 세포골격 조절 연구 및 세포 형태 분석에 적합.

카탈로그번호
OSC00055G-500UG
판매단위
pk
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마지막 업데이트 2025. 08. 02. 오전 03:26
Thermo Fisher Scientific OSC00055G-500UG Cofilin 1 Polyclonal Antibody 500 ug pk판매 단위 pk ·
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723,400원VAT 포함 795,740원

Thermo Fisher Scientific · Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 10–50 µg/mL -
Immunohistochemistry (IHC) 10–50 µg/mL -
Miscellaneous PubMed (Misc) - View 2 publications

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Published Species Not Applicable
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide from the internal part of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to an immunogenic carrier protein
Conjugate Unconjugated
Form Lyophilized
Concentration Not Determined
Purification Ammonium sulfate precipitation
Storage Buffer PBS
Contains No preservative
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Reconstitute in 500 µL of sterile water and centrifuge to remove any insoluble material.
  • The antigen is homologous in rat and mouse.
  • Specificity: Cofilin-1.

Target Information

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. It regulates actin cytoskeleton dynamics and is essential for normal mitosis and cytokinesis. Cofilin plays a key role in maintaining cell morphology and cytoskeletal organization, and is required for the regulation of atypical chemokine receptor ACKR2 trafficking to the cell membrane, enhancing chemokine uptake and degradation. It is also necessary for neural tube morphogenesis and neural crest cell migration.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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