Thermo Fisher Scientific CAV1 Polyclonal Antibody
Caveolin-1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, 4°C 또는 -20°C 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- OSC00057G-500UG
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 30–80 of human Caveolin-1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in many species including rat and mouse.
- Specificity: Caveolin-1.
Target Information
Caveolin-1 (CAV1) is a scaffolding protein within caveolar membranes. It interacts with G-protein alpha subunits and regulates their activity. Caveolin-1 is involved in T-cell receptor (TCR) mediated activation and co-stimulatory signaling. It binds with DPP4, inducing T-cell proliferation and NF-kappa-B activation in a TCR/CD3-dependent manner.
Mutations in the CAV1 gene can lead to congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts and neurodegeneration syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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