Thermo Fisher Scientific Histone H2B Monoclonal Antibody (C.362.2)
히스톤 H2B 단백질을 특이적으로 인식하는 Mouse IgG1 모노클로날 항체. Western blot 및 ChIP assay에 최적화됨. 인간, 마우스, 랫, 제브라피쉬 등 다양한 종에 반응. 고순도 친화 크로마토그래피 정제 및 안정한 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: View 1 publication
ChIP Assay (ChIP)
- Tested Dilution: 1.5 µg/1x10^6 cells
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat, Zebrafish |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.362.2 |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminal residues of histone H2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 12 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982286 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other histones.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.
Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4).
These nucleosomes further compact DNA into chromatin, limiting DNA accessibility to cellular machineries that require DNA as a template.
Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
H2B has a broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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