Thermo Fisher Scientific ALOX5 Monoclonal Antibody (G.590.2)
ALOX5 단백질을 인식하는 Rabbit 모노클로날 항체로, Western blot, IHC, IP에 사용 가능. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G.590.2 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Ile168 of human 5-lipoxygenase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 45 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10988013 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis.
Leukotrienes are arachidonic acid metabolites implicated in inflammatory responses such as asthma, arthritis, and psoriasis.
This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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