Thermo Fisher Scientific ACVRL1 Polyclonal Antibody
Human ACVRL1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 고순도 항원 친화 크로마토그래피 정제. PBS/BSA/glycerol buffer로 안정적 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific ACVRL1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 311–503 of Human Activin A Receptor Type II-like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544953 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7
- Predicted reactivity: Mouse (95%), Rat (96%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands.
ACVRL1 has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by bone formation in muscles, tendons, and other connective tissues, as well as Epicanthus.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-27477_ACVRL1_P37023-1_Rabbit.svg, PA5-27477_ACVRL1_P37023-1_Rabbit_PDP.jpeg)
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