Thermo Fisher Scientific Complement Factor H Recombinant Rabbit Monoclonal Antibody (JA52-13)
Recombinant rabbit monoclonal antibody (clone JA52-13) specific for human Complement Factor H. Validated for WB, IHC(P), and ICC/IF. Offers high specificity, lot-to-lot consistency, and stable liquid formulation for research use.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA52-13 |
| Immunogen | Synthetic peptide within Human Factor H (aa 131–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809991 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, followed by screening to select the best production candidates.
Key advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Factor H is a serum protein that functions as an inhibitor in the complement activation system. It regulates C3/C5 convertase activity by dissociating its subunits and serves as a cofactor for Factor I enzyme activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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