Thermo Fisher Scientific N-cadherin Polyclonal Antibody
Thermo Fisher Scientific의 N-cadherin Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
| Flow Cytometry (Flow) | 1:50 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to Human N-Cadherin aa 391–440 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802717 |
Target Information
N-cadherin is a 140 kDa transmembrane protein that mediates calcium-dependent intercellular adhesion. It belongs to the cadherin family, which regulates morphogenetic movements and cell surface adhesion through homotypic interactions. N-cadherin’s function depends on its association with the actin cytoskeleton via catenin proteins, and this interaction is regulated by phosphorylation of beta-catenin. The protein includes five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail, playing a critical role during gastrulation and in establishing left-right asymmetry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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