
Thermo Fisher Scientific ALS Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
ELISA (ELISA)
1 µg/mL
Product Specifications
Species Reactivity
Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_0049611) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
ALS,
uniProtId:
P35858-1,
ncbiNodeId:
9606,
antigenRange:
396-605,
antigenLength:
605,
antigenImageFileName:
PA5-87723_ALS_P35858-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-87723_ALS_P35858-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1.89 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804368
Product Specific Information
Immunogen sequence: SCLGRIRPHT FTGLSGLRRL FLKDNGLVGI EEQSLWGLAE LLELDLTSNQ LTHLPHRLFQ GLGKLEYLLL SRNRLAELPA DALGPLQRAF WLDVSHNRLE ALPNSLLAPL GRLRYLSLRN NSLRTFTPQP PGLERLWLEG NPWDCGCPLK ALRDFALQNP SAVPRFVQAI CEGDDCQPPA YTYNNITCAS PPEVVGLDLR DLSEAHFAPC; Positive Samples: Mouse lung, Rat liver; Cellular Location: extracellular space
Target Information
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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