Thermo Fisher Scientific Cathepsin O Polyclonal Antibody
Human Cathepsin O 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용 가능. 고순도 항원 친화 크로마토그래피로 정제된 액상 항체이며, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 41–279 of Human Cathepsin O |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545761 |
Product Specific Information
- Recommended positive controls: HepG2, HCT116
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The cathepsin family of proteolytic enzymes includes several protease classes:
- Cysteine proteases: Cathepsins B, L, H, K, S, O
- Aspartyl proteases: Cathepsins D, E
- Serine protease: Cathepsin G
Most cathepsins are lysosomal and participate in cellular metabolism, peptide biosynthesis, and protein degradation.
Cathepsin O retains the structural features of cysteine proteinases, including the active site cysteine residue involved in covalent intermediate formation during peptide hydrolysis. It functions as an endoproteinase that may contribute to extracellular matrix degradation.
Expression is abundant in ovary, kidney, and placenta, with lower levels in thymus and skeletal muscle.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-28285_Cathepsin_O_P43234-1_Rabbit.svg, PA5-28285_Cathepsin_O_P43234-1_Rabbit_PDP.jpeg)
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