Thermo Fisher Scientific Phospho-GAB2 (Tyr452) Monoclonal Antibody (J.629.4)
Phospho-GAB2 (Tyr452) 단백질을 검출하는 Rabbit Monoclonal 항체로, Western blot에 적합합니다. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J.629.4 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr452 of human Gab2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10981424 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene belongs to the GRB2-associated binding protein (GAB) family. These proteins contain a pleckstrin homology (PH) domain and interact with SHP2 tyrosine phosphatase and GRB2 adapter protein. They function as adapters transmitting various signals in response to cytokines, growth factors, and antigen receptor stimulation in T- and B-cells. The encoded protein is a principal activator of phosphatidylinositol-3 kinase upon activation of the high-affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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