Thermo Fisher Scientific PLC gamma 1 Polyclonal Antibody
PLC gamma 1 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 IHC(P) 검증 완료. 고순도 항원 친화 크로마토그래피 정제. 인산화 신호 전달 연구에 적합. 연구용 전용 제품.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from internal segment of human PLC gamma 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Crude extract of B. cereus.
Target Information
The mammalian Phospholipase Cγ (PLCγ) family includes two closely related proteins, PLCγ1 and PLCγ2. These isozymes share core structural domains and possess unique arrangements including an additional PH domain, two SH2 domains, and one SH3 domain.
In response to extracellular stimuli such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), producing the second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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