Thermo Fisher Scientific CD89 Monoclonal Antibody (A59), PE
CD89 (FCAR) 단백질을 인식하는 마우스 단클론 항체로, PE 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 인간 및 비인간 영장류 시료에 반응하며, IgA 수용체 연구에 활용됩니다. 4°C 암소 보관, 동결 금지.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Non-human primate, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A59 |
| Immunogen | Ag8.653 myeloma cells expressing CD89 (FCAR), UniProt ID: P24071-1, antigen range: 1–287 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745506 |
Available Formats
- Unconjugated: MA5-28548
- FITC: MA5-28546
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD89, a 55–100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes, and macrophages.
Recommended dilution: 10 µL for 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
The CD89 (FCAR) gene encodes a receptor for the Fc region of IgA, belonging to the immunoglobulin gene superfamily. This transmembrane glycoprotein is expressed on myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils. It mediates immune responses to pathogens by binding IgA-opsonized targets and triggering processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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