Thermo Fisher Scientific ATOH1 Polyclonal Antibody
ATOH1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. Human 및 Mouse 시료에서 반응하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%) 항체로 신경세포 분화 연구에 활용 가능.
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- PA576016
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human MATH1 (ATOH1, UniProt ID: Q92858-1, amino acids 1–354) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719744 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The Drosophila atonal gene encodes a protein with basic helix-loop-helix (bHLH) domains essential for nervous system development. Its mammalian homolog, MATH-1 (also known as Atoh1, Ath1, or HATH-1), is a 351 amino acid HLH transcription factor structurally related to the Drosophila atonal protein. In mice, MATH-1 expression begins around embryonic day 9.5, initially in cranial ganglia and the dorsal central nervous system. Expression later localizes to the external granular layer of the cerebellum by day 18 and becomes undetectable in the adult nervous system. MATH-1 is implicated in neural cell differentiation through activation of E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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