Thermo Fisher Scientific Calumenin Polyclonal Antibody
Calumenin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. PBS/glycerol buffer에 저장되며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human Calumenin (aa 1–315) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2719748 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Calumenin is a 315 amino acid Ca²⁺-binding protein belonging to the CREC, EF-hand family. It is secreted and localized in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. Calumenin contains six Ca²⁺-binding (EF-hand) motifs and interacts with serum amyloid P component (SAP) in the presence of calcium. Together, they may contribute to immune defense and amyloid formation in various tissues. Calumenin also inhibits the vitamin K-dependent γ-carboxylation system and may play roles in thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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