Thermo Fisher Scientific ATP1B1 Monoclonal Antibody (464.8 (aka 8A))

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Immunocytochemistry (ICC/IF)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Bovine, Dog, Chicken, Hamster, Human, Pig, Rabbit, Rat, Xenopus

Published species

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

464.8 (aka 8A)

Immunogen

Purified Na,K-ATPase from rabbit renal outer medulla. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ATP1B1,uniProtId:Q9TT37-1,ncbiNodeId:9986,antigenRange:1-303,antigenLength:303,antigenImageFileName:MA1-16732_ATP1B1_Q9TT37-1_House_mouse.svg,antigenImageFileNamePDP:MA1-16732_ATP1B1_Q9TT37-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2060998

Product Specific Information

This antibody does not react with mouse samples.

Target Information

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.