Thermo Fisher Scientific GNA11 Polyclonal Antibody
Thermo Fisher Scientific의 GNA11 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot 및 IHC(파라핀) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, PBS/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human GNA11 (UniProt ID: P29992-1, amino acids 1–359) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720405 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β, and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines, and sensory stimuli. Over 20 known Gα subunits are classified into four families — Gα(s), Gα(i/o), Gα(q), and Gα(12) — based on structural and functional similarities. Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, as substitution with phenylalanine disrupts receptor interaction and abolishes ligand-induced IP3 formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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