Thermo Fisher Scientific FBXO32 Polyclonal Antibody
FBXO32 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 근육 위축 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human FBXO32 (UniProt ID: Q969P5-1, amino acids 1–355) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720407 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
FBXO32 encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. These proteins are components of the SCF ubiquitin ligase complex, which mediates phosphorylation-dependent ubiquitination.
FBXO32 belongs to the Fbxs subclass and is highly expressed during muscle atrophy. Mice deficient in this gene are resistant to atrophy, making FBXO32 a potential drug target for muscle atrophy treatment.
Alternative splicing generates two transcript variants encoding isoforms of different sizes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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