Thermo Fisher Scientific Cdc7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CDC7 for IHC (Paraffin) applications. Recognizes CDC7-Related Protein Kinase involved in G1/S transition and DNA replication. Supplied as liquid, unconjugated, purified by antigen affinity chromatography. Suit...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 6.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from kinase domain of human CDC7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2078369 |
Product Specific Information
PA1-24588 detects CDC7-Related Protein Kinase (CDC7L1) in human samples.
Target Information
CDC7 is a cell division cycle 7 homolog protein critical for the G1/S transition and initiation of DNA replication. It is expressed in many normal tissues, but overexpression may be associated with neoplastic transformation in certain tumors and cell lines. The CDC7/DBF4 kinase promotes S phase progression by alleviating inhibitory activity in Mcm4, integrating several protein kinases. Multiple alternatively spliced transcript variants encoding the same protein have been detected.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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