Thermo Fisher Scientific Cdc7 Polyclonal Antibody
Human CDC7 단백질을 인식하는 rabbit polyclonal antibody로, IHC(P)에서 5.2 µg/mL 농도로 검증됨. 세포 분열 및 DNA 복제 연구에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.1% sodium azide 포함, 장기 보관 시 -20°C 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC(P)): Tested dilution 5.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from kinase domain of human CDC7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2078378 |
Product Specific Information
PA1-24587 detects CDC7-Related Protein Kinase (CDC7L1) in human samples.
Target Information
CDC7 is a cell division cycle 7 homolog protein critical for the G1/S transition and initiation of DNA replication. It is expressed in many normal tissues, but overexpression may be associated with neoplastic transformation in some tumors and transformed cell lines.
CDC7/DBF4 kinase promotes S phase progression by alleviating inhibitory activity in Mcm4. The yeast homolog is also essential for DNA replication initiation. Multiple alternatively spliced transcript variants encoding the same protein have been detected.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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