Thermo Fisher Scientific PRMT5 Recombinant Rabbit Monoclonal Antibody (ST51-06)
PRMT5 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체(ST51-06). Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며 높은 특이성과 재현성을 제공. 동물 유래 성분이 없는 포뮬레이션으로 일관된 품질 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:5,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ST51-06 |
| Immunogen | Synthetic peptide within Human PRMT5 (aa 48–91) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809449 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
PRMT5 (Protein Arginine N-Methyltransferase 5) is an enzyme that catalyzes the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for MMA formation.
It mediates symmetrical dimethylation of arginine residues in small nuclear ribonucleoproteins Sm D1 and Sm D3, essential for snRNP core particle assembly and biogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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