Thermo Fisher Scientific KLC1 Polyclonal Antibody
KLC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보존. 인체, 마우스, 랫트 반응성.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLC1 (Accession Q07866), corresponding to amino acid residues S134–E184 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852188 |
Product Specific Information
Antibody detects endogenous levels of total KLC1.
Target Information
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, transporting various cargos along microtubules toward their plus ends.
The heavy chains provide motor activity, while the light chains bind to cargos.
KLC1 encodes a kinesin light chain family member that associates with kinesin heavy chain through an N-terminal domain.
Six tetratricopeptide repeat (TPR) motifs are involved in binding cargos such as vesicles, mitochondria, and the Golgi complex.
Kinesin light chains function as adapter molecules rather than motors.
Although previously named “kinesin 2,” this gene is not part of the kinesin-2 subfamily.
Extensive alternative splicing produces isoforms with different C-termini, proposed to bind different cargos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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