Thermo Fisher Scientific L-Plastin Polyclonal Antibody
L-Plastin 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LCP1 (Accession P13796), corresponding to amino acid residues M1–E33 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852194 |
Product Specific Information
Antibody detects endogenous levels of total Plastin L.
Target Information
L-plastin is a leukocyte-specific actin bundling protein belonging to the fimbrin family. It contains two actin-binding domains and two EF-hand calcium-binding domains. Phosphorylation occurs at the serine residue in its headpiece region in response to inflammatory stimuli. L-plastin may regulate integrin-mediated adhesion in leukocytes and is expressed in most human cancer cell lines derived from solid tumors. Its expression is upregulated by testosterone in androgen receptor-positive prostate and breast cancer cells through three androgen receptor binding elements located upstream of the gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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