Thermo Fisher Scientific UGT1A4 Polyclonal Antibody
UGT1A4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UGT1A4 (Accession P22310), corresponding to amino acid residues A26–T76 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852187 |
Product Specific Information
Antibody detects endogenous levels of total UGT1A4.
Target Information
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules—such as steroids, bilirubin, hormones, and drugs—into water-soluble, excretable metabolites.
The gene locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are pseudogenes. Each of the remaining nine 5′ exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini.
Each first exon encodes the substrate binding site and is regulated by its own promoter. This enzyme has some glucuronidase activity toward bilirubin, although it is more active on amines, steroids, and sapogenins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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