Thermo Fisher Scientific ATF1 Monoclonal Antibody (OTI2C2), TrueMAB
ATF1 단백질을 인식하는 Mouse monoclonal 항체로, Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, 액상형으로 제공됨. Affinity chromatography로 정제되어 고순도 보장. 연구용으로 세포 성장 및 전사 조절 연구에 적합.
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- TA807623
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C2 |
| Immunogen | Full length human recombinant protein of human ATF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an activating transcription factor (ATF1), a member of the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates the expression of downstream target genes involved in growth, survival, and other cellular activities. The protein is phosphorylated at serine 63 by several serine/threonine kinases, enhancing its transcriptional activity and contributing to cell transformation. Chromosomal translocations involving this gene and FUS (chromosome 16) or EWSR1 (chromosome 22) generate chimeric proteins associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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